Best B12 Supplement of 2019 – Top Reviews

We tested and reviewed some of the best B12 supplements on the market. We found that Advanced Vitamin B12 Complex Spray seems to work the best. It’s a readily available spray formulation which pushes things through quickly and easily. Of course, if you prefer pills or you’re on a tight budget then we’ve still got something for you.

1. Advanced Vitamin B12
Best overall: Vitamin B12 Complex Spray

If you’re in need of a B12 supplement for energy during the day, this is the one you’ve been looking for. It’s easy to use, fairly priced, and the convenience of this spray formulation just can’t be beat. It tastes awesome too.

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Top 5 B12 Supplements

Name Type Rating
Advanced Vitamin B12 Complex Spray Spray 5/5 Check Price
Vitamin B12 Sublingual Liquid Drops Liquid 4.5/5 Check Price
Vitamin B12 Sublingual Methylcobalamin 3000 mcg Liquid 4/5 Check Price
Nature's Bounty Quick Dissolve Sublingual Tablets 4/5 Check Price
OneNaturals Vitamin B12 Methylcobalamin Pills 3.5/5 Check Price

1. Best Overall B12 Supplement

1. Advanced Vitamin B12

Advanced Vitamin B12 Complex Spray

Product Rating 5 /5
Reviewed by:

We can’t say enough about this spray. Of all of the variations we tried out, the sprays seemed to be the easiest to keep on your person while working extremely quickly. It delivers an impressive 1mg of methylcobomalin with each spray.

This easily absorbed form of vitamin B12 is ideal in pretty much all cases but it’s particularly ideal for sprays.

The convenience factor of spray formulations simply can’t be matched. Lift it up and spray it in your mouth and you’ll quickly receive the benefit you need to get through the day. It’s not ideal for people who have a deficiency, but for those looking for a quick burst of energy it works great.

In addition to all of the benefits and the convenience… it also tastes great.

Pros and Cons
  • Easy to use spray bottle fits in bags and pockets
  • Provides nearly instant energy
  • Contains other vitamins as well
  • Contains methylcobomalin for superior absorption
  • Not good for those with deficiencies
  • Rather expensive if you use it often

2. Best B12 Supplement for Deficient People

2. Vitamin B12 Sublingual

Vitamin B12 Sublingual Liquid Drops

Product Rating 4.5 /5
Reviewed by:

If you’re actually deficient on B12 then you need something strong that you can take daily. That pretty much puts sprays at the bottom of the list, since they’re usually formulated for quick energy rather than sustaining serum levels.

This particular supplement contains 5mg of methylcobomalin. That makes it ideal for those who have deficiencies although it may be a bit much for the average person.

It’s also vegan-friendly, making it perfect for those who live that lifestyle. B12 deficiencies are common in the vegan population due to its rarity in plant sources, so it’s a welcome addition that can keep energy levels high and allow you to receive the benefits you need ethically.

The drops have an awesome taste as well, avoiding the medicine-like perception that many people have with their supplements.

This is the perfect formulation for those who have low levels of B12 due to their diet or conditions. On the other hand, it may be a bit too much for the average person but if you respond well to B12 when it comes to energy it’s worth a shot and won’t hurt you.

Pros and Cons
  • Extremely high dose supplement
  • Contains methylcobomalin for superior absorption
  • Drops taste great
  • Easy to dose liquid formulation
  • Very expensive
  • Liquid form isn’t all that convenient on the go

3. Best Budget Liquid B12 Supplement

3. Vitamin B12 Sublingual

Vitamin B12 Sublingual Liquid Drops Methylcobalamin 3000 mcg

Product Rating 4 /5
Reviewed by:

While the dose isn’t quite as high as our previous liquid, but this 3mg dropper bottle is perfect for those who want to use a liquid on a tighter budget. Liquid formations tend to run a bit high on the pricing scale and those which don’t tend to use inferior formulations.

Luckily, we found this one, which contains methylcobomalin and is perfectly priced for the average household. Each dose contains a high, but not too high, dose of B12. It can be used by those who are deficient as well as those who are planning on using it to get some energy.

These drops are extremely high-quality despite the lower pricing as well. The bottle comes with a convenient dropper for dosing and it’ll absorb quickly under the tongue.

If you need a B12 liquid supplement then you’re in luck with this one. Snatch these drops up and enjoy all of the benefits without the higher cost.

Pros and Cons
  • Easy to dose liquid
  • Contains an easily absorbed form of B12
  • Great price
  • Provides lasting energy quickly and easily
  • A bit too sweet and syrupy for our tastes
  • Dosing exactly can be hard with no measure on the dropper

4. Best Sublingual B12 Supplement

4. Natures Bounty Quick

Nature's Bounty Quick Dissolve

Product Rating 4 /5
Reviewed by:

If you’re looking for something convenient but don’t want to go all out on a spray, then these sublingual tablets are exactly what you’re looking for.

Unlike liquids, you can easily keep a couple of these in your bag or car and take them as needed. All you have to do is stick them under the tongue and they’ll dissolve and hit the bloodstream quickly, bringing you the energy you need to get through a long day.

They’ve got a natural cherry flavoring as well, so you don’t need to worry about a nasty aftertaste when you take them.

On the other hand, they’re a bit lower in dosage than many of our favorites, but it’s still an easily absorbed form of B12 and they hit pretty quickly.

If you’re looking to save some money but want to step up the convenience over liquid formulations, then pick up these quick-absorbing sublingual tablets.

Pros and Cons
  • Quick dissolving tablets for easy dosing
  • More accurate and convenient than liquids
  • Contains the best form of B12
  • Cheap and readily available
  • Less convenient than sprays
  • Some people really didn’t like the taste

5. Best Budget B12 Supplement

5. OneNaturals Vitamin B12

OneNaturals Vitamin B12 Methylcobalamin

Product Rating 3.5 /5
Reviewed by:

Pills aren’t the most popular form of B12 supplementation around. They’re great for those on a tight budget however, and these pills contain enough to make them a great daily supplement.

The only real problem is that they’re not super suitable for quick energy.

These pills are cheap and contain a full milligram of B12. If you’re trying to keep your levels sustained then pick them up and take two or three once a week in order to maintain higher levels.

Other than that, these aren’t really the first line choice for anyone with the money for the other formulations.

On the other hand, if you want to keep your supplement costs low, then these pills are definitely the best way to do it. They make a perfect daily supplement, they just aren’t the quickest to hit and the dose is a bit low.

Pros and Cons
  • Super cheap
  • Readily available
  • High quality control with OneNaturals
  • Contains a good form of B12
  • Not the best form for most people
  • Really only suitable as a daily supplement

Who Needs a B12 Supplement?

One of the most common supplements used in the modern day is vitamin B12. This essential nutrient is responsible for providing energy, and many people find their diets quite lacking in it over time. The problem is that there are so many different brands of it available, and it seems like everyone promises that their supplement works better than the rest.

Let’s take a look at five of our favorites, and then we’ll dive in and see if we can’t make things just a little bit clearer for you when it comes time to pick your supplement.

Vitamin B12 is commonly sold as an energy supplement, and in that role it works amazingly well. If you’re feeling fatigued during the day then it might be exactly what you need to give you the leg up to be more productive and generally feel better during the day.

There’s a hidden demographic, however, who really need the stuff: vitamin B12 is only naturally found in animal products such as meat and dairy. That means it’s essential for vegans and vegetarians to supplement their diets with it in order to avoid the problems inherent with a deficiency of this vital nutrient.

People who drink regularly are also in need of B-vitamins, although you may be better off seeking a B-complex if that’s the case.

There’s some controversy over dietary sources of B12, but chances are that if you’re not taking a supplement then you should be if you’re vegan or anemic.

Other than that, the following symptoms are usually a good indicator of a B12 deficiency:

  • Weakness and fatigue
  • Heart palpitations
  • Shortness of breath
  • Smoothed out tongue
  • Depression
  • Tingling in muscles
  • “Brain fog”

If you’re experiencing any of the above then you may want to try giving a B12 supplement a shot. If you’re not, but just want a source of clean energy, B12 works as well, although you may be best served by a complex vitamin instead of a strict B12 supplement.

What Is Vitamin B12?


Vitamin B12 is an essential nutrient, since it acts as a catalyst in several vital chemical interactions within your body.

It’s actually the most complex of the eight B-vitamins by a long shot, and the primary source of it is through bacterial reactions since almost all creatures lack the ability to create it themselves.

The chemical is called cobalamin, since the molecule contains the rare metal cobalt at it’s center.

While many foods are reputed to contain it, such as sea weed, scientific investigation usually finds that they actually contain analogues which are useless to the human body. This means that deficiencies must be treated with supplements.

Since it has an integral role in energy production it’s one of the most common vitamin supplements around. It can be found in energy drinks, energy bars, and fortified foods as well. It’s still recommended that vegans and vegetarians use it as a supplement, however.

It’s produced in bacterial vats from which it is extracted, which means that it can still be considered “vegan” as long as you’re aware of the source you’re looking at.

Which Type of B12 Absorbs Best?

There are two major types of vitamin B12, methylcobomalin and adenosyclcobomalin. Both of them are biologically active, meaning that your body can use the, but methylcobomalin absorbs much better.

Unlike most vitamins, the body doesn’t readily accept B12 due to its complexity, so if you’re looking for a supplement it’s important to make sure that you’re able to absorb the type readily, and it means that various dosages of different types of B12 will have different effects.

eThere are a few other types as well, cyanocobomalin being one of the most common forms but not being readily absorbed by the body.

Look for formulations which contain methylcobomalin for the best results. Less will do it in that case.

You can pretty much ignore the idea of “organic B12” since pretty much every source of it could fall under that label.

Types of B12 Supplements Available

There are a ton of different preparations of B12 on the market, many of them being in the usual pill form but there are many different preparations available.

Pills are the traditional way and seem to work just as well, but many people have absorption issues. If you’re deficient despite taking a supplement, then you’re going to want to try another form.

Specifically for pills, however, you may want to snatch up a B-complex instead of a straight B12 supplement. This way you can get even more nutrients within a single pill and most of the B vitamins have similar properties although they’re easier to get through your diet.

Sublingual tablets are another good option, especially for those who might have intestinal problems absorbing. These tablets dissolve underneath the tongue, which theoretically has a higher bioavailability than the normal oral route.

Be careful with the extras, as some of the sugar substitutes used can cause gastrointestinal distress in those who are sensitive to them. Just keep an eye on the ingredients list if you know that you have trouble tolerating these chemicals anyways.

There are also liquid types available. These are usually used similarly to sublingual tablets, just place them under the tongue and let them absorb for the best results.

The final form available commonly are sprays, which you simply squirt in your mouth in order to receive the supplementation.

All of these methods are pretty well proven and stand the test of time. At the end of the day which form you use will depend mainly upon your own personal tastes, but we recommend sprays and sublingual tablets.

There is still some debate as to whether sublingual absorption is necessary for most people, since pills and sublingual methods seem to have roughly comparable absorption rates in those who aren’t deficient in stomach acid or having other issues with their GI tract.

Sublingual tablets are definitely the easiest option for most people, however.

The Dosage Question


B12 is a remarkably safe vitamin, with extra being excreted readily by the body. The recommended dose, by the NIH, is around 2.4 micrograms a day. Most supplements supply several times this amount so it’s really not an issue.

On the other hand, those who suffer from conditions which prevent it from absorbing are best off with a single larger dose, roughly 2mg, once per week in order to maintain the needed levels in the bloodstream.

How Often Should I Take a B12 Supplement?

If you’re not using it for short term energy purposes, then you’ll find that B12 supplements are best taken once per day.

For short term energy production you can use it as needed, within reason, and your body will get rid of the rest through your urine. If you’re peeing bright yellow, then you’re probably taking too much.

Once a day is fine, if you have a real deficiency then you may want to take a couple of milligrams total once per week in order to get more absorption. Those who are dangerously low should probably see a doctor, who can prescribe shots and patches for usage every few months.

How Safe is Vitamin B12?

There are fifty years of safety behind the usage of vitamin B12 in higher doses. There isn’t a real “upper limit” on the amount you should be taken in, which means that it’s remarkably hard to overdose on the vitamin.

Single, extremely high doses, are even used as a treatment for cyanide poisoning in many cases.

There’s just no evidence that B12 is dangerous at any dose, so dose away. Your body should be able to handle it in most cases.

Vitamin B12 does have some serious interactions with medication, however, so check with your doctor before taking it if you’re on any prescription medications.

So What is the Ideal Supplement?


Honestly, for those without any of the aforementioned disorders, a high-quality pill in the 2-3mg range is probably best. They’re simple, effective, and easy to remember to take.

But really, it depends on what you’re planning on doing.

Serious Deficiencies

If you have one of the disorders which makes it hard to metabolize B12, then you’re going to need a bit of thought into what you’re going to use.

In this instance high dose sublingual tablets are probably the best way to go. You can take extra once a week to help maintain higher levels and not suffer from the deficiency quite as much.

Vegans and Vegetarians

If you’re on a special diet, then you may want to go with a high dose pill. Take it once per day in order to make sure that you don’t end up running low on energy due to insufficient nutrient intake.

You may also want to take a separate multivitamin in order to maintain levels of other nutrients which are hard to get, any one will do and there’s no need to worry about getting too much B12 due to the mixture.

Higher Energy

If you’re a high-responder to B12, then you may want to snatch up one of the high-dose B12 sprays on the market. These sprays kick in quickly and can provide a lot of energy.

Even better, they’re convenient to carry on your person which means you can have them at hand when you need them the most.

A High Benefit Vitamin

Vitamin B12 isn’t going to work miracles, but it can feel like it if you’ve been deficient for a long time. If you’re feeling low on energy it’s one of the smallest changes you can make in order to enjoy a serious effect.

You can look forward to some of the following benefits with increased vitamin B12 intake:

  • Heightened energy levels
  • Lessened depression symptoms
  • Heightened metabolism of proteins

The amount of things that B12 helps out may as well be the entire human body. This is an essential, extremely important nutrient that we’re talking about. The benefits are pretty much endless.

B12 protects from cancer and heart disease, and low levels of it are even implicated in Alzheimer’s disease.

It’s also implicated in helping with the following conditions:

  • It can help prevent strokes
  • It helps with hypertension by helping your blood pressure maintain equilibrium
  • It lowers cholesterol
  • It makes your hair and nails healthier through helping with keratin production
  • It aids in keeping your digestive system functioning properly
  • It aids in keeping your brain alert and ready to go

Basically: if you’re not getting enough vitamin B12, then you’re no in the best shape you can be in.

There’s not a lot that this vital nutrient doesn’t help, and since it’s so safe to use pretty much everyone could use a supplement to ensure they’re at the best they can be.

best b12 vitamins


Whether you’re looking to correct a dietary imbalance or just have more energy through the day, you should be looking for the best B12 supplement you can. There’s something out there which is suitable for everyone, from sprays to sublingual tablets to liquids with high concentrations.

Pick up your supplement today and you’re going to experience a heightened level of well-being that you never really thought possible. Increased energy, a faster metabolism, and disease prevention are all available in a spray, tablet, or pill that’s just right for you.

Snatch up what you need now, these supplements are cheap, safe, and highly effective.


Max Perzon

About Max Perzon

Max is a 28 year old blogger from Sweden that loves to review home related products, and now writes for Homethods full-time. Read more about him